Research & Education
Our research spans tissue quality assessment, molecular biology, and training the next generation of neuropathologists.
Ongoing Research Projects
Effect of Post-mortem Interval (PMI) on Histopathological and IHC Assessment
In preparation for manuscriptBrain tissue with different PMI (1 to >30 hrs) was assessed for an objective decay score on histopathology and different immunohistochemistry related to basic structure and enzymes related to ROS metabolism.
Effect of PMI on DNA and RNA Integrity
In preparation for manuscriptBrain tissue assessed for RNA and DNA integrity. Assessment of different regions of mRNA of Cytochrome C1 (CYC1) with qRT-PCR.
Pathobiology of Cerebral Small Vessel Disease (CSVD)
In progressExpression profiling of different molecular markers related to ferroptosis-mediated cell death in CSVD cases.
Multimodal Evaluation of RNA Integrity and Tissue Quality
In progressComprehensive assessment of RNA integrity and tissue quality in human postmortem brain specimens across varying post-mortem intervals in a tropical Indian brain biobank.
Education & Training
Training MD Pathology residents pursuing their degree on brain autopsy, anatomical dissection, histopathological assessment, and storage of brain tissue.
Development of skill and competence of MD Pathology residents for performing brain autopsy and dissection independently.
Preliminary diagnosis of gross and microscopic pathology during autopsy sessions.
Dissection images & detailed procedure overview — coming soon.